Aloe -emodin CAS 481-72-1

Dayang Chem (Hangzhou) Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm aloe-emodin cas 481-72-1 hauv Suav teb, tshwj xeeb hauv kev muab cov tshuaj zoo tshaj plaws. Txais tos rau cov lag luam wholesale bulk aloe-emodin cas 481-72-1 ua nyob rau hauv Suav teb nov thiab tau pricelist los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Khoom Taw Qhia:

1.     Specification

Qhov tseeb specifications thiab COA yuav raug xa mus raws li qhov kev thov.

2.     Ntim & shipping

3.     Daim ntawv thov

Aloe emodin yog hydroxyanthraquinone tam sim no nyob rau hauv Aloe vera nplooj, muaj ib qho tshwj xeeb hauv vitro thiab hauv vivo antitumor kev ua si.IC50 tus nqi: Lub Hom Phiaj: hauv vitro: aloe -kev kho mob emodin coj mus rau dissociation ntawm tshav kub shock protein 90 (HSP90) thiab ER thiab nce ER ubiquitination. Protein fractionation cov txiaj ntsig qhia tias aloe-emodin nyiam ua rau cytosolic ER degradation. Aloe-emodin, lub ntuj tsim muaj nyob rau hauv aloe, inhibited ob qho tib si proliferation thiab anchorage- ywj siab loj hlob ntawm PC3 hlwb. Kev soj ntsuam cov ntsiab lus ntawm cov protein tau qhia tias kev ua kom cov dej ntws hauv qab ntawm mTORC2, Akt thiab PKC, yog inhibited los ntawm aloe- kho emodin. Rub-down assay thiab in vitro kinase assay cov txiaj ntsig tau qhia tias aloe-emodin tuaj yeem khi nrog mTORC2 hauv hlwb thiab inhibit nws txoj haujlwm kinase . Ntawm peb cov tshuaj anthraquinone derivatives, aloe-emodin, nrog qis cytotoxicity pom tias muaj concentration-nyob ntawm kev txo tus kab mob-induced cytopathic effect thiab inhibiting replication of influenza A hauv MDCK cells. Galectin-3 kuj tiv thaiv kab mob khaub thuas A tus kab mob replication. Proteomic tsom xam ntawm cov hlwb kho tau qhia tias galectin-3 nce- kev tswj hwm raws li ib qho kev tiv thaiv kab mob khaub thuas A tus kab mob los ntawm aloe -emodin. Txij li thaum galectin-3 nthuav tawm cytokine-zoo li kev tswj hwm ntawm JAK/STAT txoj hauv kev, aloe-emodin kuj tau rov qab kho NS1-inhibited STAT1-cov tshuaj tiv thaiv kab mob sib kis hauv cov kab mob sib kis (STAT1) ntawm kev sib cuam tshuam (piv txwv li, Cov ntsiab lus stimulation teb (ISRE)-tsav txhawb nqa, RNA-dependent protein kinase (PKR) thiab 2'5',-oligoadenylate synthetase (2'5',-OAS) qhia . AE downregulated mRNA kev qhia thiab kev txhawb nqa / gelatinolytic kev ua ntawm Matrix Metalloproteinase (MMP)-2/9, nrog rau RhoB qhia ntawm qib noob thiab protein. AE suppressed lub nuclear translocation thiab DNA khi ntawm NF-B .in vivo: Aloe-emodin kuj tau nthuav tawm cov teebmeem qog nqaij hlav hauv vivo hauv tus qauv athymic liab qab nas.

4.     Spectrum

5.     Cov ntawv txheeb

1. Kev sib raug zoo ntawm kev txo cov peev xwm thiab inhibitions ntawm Epstein-Barr virus activation los ntawm anthraquinone derivatives.Bioorg. Med. Chem. Lett.   18 , 4106-9, (2008)
2. Hauv vitro inhibition ntawm Streptococcus mutans biofilm tsim ntawm hydroxyapatite los ntawm subinhibitory concentrations ntawm anthraquinones.Antimicrob. Tus neeg saib xyuas Chemother.   51 , 1541-4, (2007)
3. High-kev sib raug zoo, tsis yog-nucleotide- tau txais kev sib tw antagonists ntawm platelet P2Y12 receptors.J. Med. Chem.   52 , 3784-93, (2009)

Cim npe nrov: Tuam Tshoj aloe-emodin cas 481-72-1 manufacturers, lwm tus neeg, Hoobkas