Tom ntej: Tolbutamide CAS 64-77-7

Dayang Chem (Hangzhou) Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm tolbutamide cas 64-77-7 hauv Suav teb, tshwj xeeb hauv kev muab cov tshuaj zoo tshaj plaws. Txais tos rau kev lag luam wholesale bulk tolbutamide cas 64-77-7 ua nyob rau hauv Suav teb nov thiab tau txais pricelist los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Khoom Taw Qhia:

1.     Specification

Qhov tseeb specifications thiab COA yuav raug xa raws li qhov kev thov.

2.     Ntim & shipping

3.     Daim ntawv thov

Tolbutamide yog thawj tiam potassium channel blocker, sulfonylurea qhov ncauj hypoglycemic tshuaj.Target: Potassium ChannelTolbutamide yog ib qho tshuaj tiv thaiv qhov ncauj uas siv rau kev kho mob uas tsis yog -insulin- nyob ntawm ntshav qab zib mellitus (NIDDM). Tolbutamide ua los ntawm stimulating hlwb ntawm pancreas kom tso tawm insulin. Sulfonylureas nce ob qho tib si basal insulin secretion thiab noj mov - txhawb kev tso tawm insulin. Tolbutamide belongs rau ib chav kawm ntawm cov tshuaj hu ua sulfonylureas. Tolbutamide inhibits ob qho tib si basal thiab cyclic AMP-stimulated protein kinase kev ua ub no thiab IC50 ntawm Tolbutamide yog 4 mM. Zoo sib xws Tolbutamide concentrations yog xav tau rau ib nrab qhov siab tshaj plaws inhibition ntawm vitro lipolysis tshwm sim los ntawm cov tshuaj hormones (norepinephrine thiab ACTH) lossis los ntawm dibutyryl cyclic AMP ntxiv rau theophylline. Tolbutamide kuj inhibits soluble thiab daim nyias nyias - khi protein kinase los ntawm canine lub plawv. Tolbutamide inhibition ntawm adipose cov ntaub so ntswg cyclic AMP-dependent protein kinase yog ib qho ua tau piav qhia txog cov tshuaj tiv thaiv lipolytic ntawm cov tshuaj no. Tolbutamide inhibits C6-glioma cell proliferation los ntawm kev nce Cx43, uas cuam tshuam nrog kev txo qis hauv pRb phosphorylation vim yog kev tswj hwm ntawm Cdk inhibitors p21 thiab p27 .

4.     Spectrum

5.     Cov ntawv txheeb

1. Cheminformatics tsom xam ntawm kev lees paub mined los ntawm cov ntaub ntawv uas piav txog tshuaj-induced siab raug mob nyob rau hauv ntau hom.Chem. Res. Toxicol.   23 , 171-83, (2010)
2. Txhais cov kev tshawb fawb soj ntsuam rau hauv kev paub hauv kev tshuaj xyuas kev nyab xeeb tshuaj--tshuaj mob siab rau kev raug mob siab rau lub siab (DILIps).J. Sci. Ind. Res.   65(10) , 808, (2006)
3. Japanese toxicogenomics project: daim ntawv thov ntawm toxicogenomics.Mol. Nutr. Khoom noj khoom haus. Res.   54 , 218-27, (2010)

Cim npe nrov: Tuam Tshoj Tolbutamide CAS 64-77-7 Manufacturers, lwm tus neeg, Hoobkas