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Fluvastatin Sodium ntsev CAS 93957-55-2

Fluvastatin Sodium ntsev CAS 93957-55-2

Fluvastatin sodium ntsev
CAS Nr .: 93957-55-2
Purity: 98.0% Min|Qhov tsos: Dawb rau tawm -dawb hmoov
Cov mis mos molecular: C24H25FNO4.Na|PIB: 434.46
Ib: 658-036-3
Cov ntsiab lus: (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid; Lescol; fluvastatin acid

Khoom Taw qhia

Dayang Chem (Hangzhou) Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm fluvastatin sodium ntsev cas 93957-55-2 hauv Suav teb, tshwj xeeb hauv kev muab cov tshuaj zoo tshaj plaws. Txais tos rau cov lag luam wholesale bulk fluvastatin sodium ntsev cas 93957-55-2 ua nyob rau hauv Suav teb nov thiab tau pricelist los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

 

Khoom Taw Qhia:

 

1.     Specification

Qhov tshwm sim

Dawb rau tawm -dawb hmoov

Assay

98.0% Min

Poob rau ziab

1.0% Max

 

Qhov tseeb specifications thiab COA yuav raug xa mus raws li qhov kev thov.

 

2.     Ntim & shipping

Ntim

R&D Qauv Loj: 1 g, 10 g, 100 g thiab 1kg lub raj mis lossis txhuas lub hnab rau kev kuaj xyuas.

Kev faib khoom thauj

Tsis tswj raws li qhov txaus ntshai zoo

Lub Sijhawm Lead

hauv Tshuag

Shipping Txoj Kev

DHL, FedEx, huab cua freight los yog hiav txwv freight

f-Fluvastatin sodium salt

s-Fluvastatin sodium salt

 

3.     Daim ntawv thov

Fluvastatin sodium yog ib qho kev sib tw inhibitor ntawm hydroxymethylglutaryl -coenzyme A reductase (HMGCR), siv los kho hypercholesterolemia thiab tiv thaiv kab mob plawv.Target: HMGCR Fluvastatin yog ib qho kev sib tw inhibitor ntawm hydroxymethylglutaryl-coenzyme A reductase (HMGCR}), cov enzymes hloov dua siab tshiab mevalonic acid, tus nqi - txwv cov kauj ruam hauv biosynthesis cholesterol. Human hepatocellular carcinoma cell (HCC) cov kev tshawb fawb qhia tias Fluvastatin induces G2 / M theem ntes. Nyob rau hauv lub xub ntiag ntawm Fluvastatin, HCC hlwb qhia qhov txo qis ntawm Bcl-2 thiab procaspase-9 qhia, thiab nce hauv Bax, cleaved caspase-3, thiab cytochrome c. Fluvastatin yog antilipemic thiab siv los txo cov roj cholesterol hauv cov ntshav thiab tiv thaiv kab mob plawv.

 

4.     Spectrum

 

 

5.     Cov ntawv txheeb

1. Dehydroepiandrosterone sulfate, ib qho tseem ceeb endogenous soj ntsuam rau kev soj ntsuam ntawm cov tshuaj - tshuaj cuam tshuam rau hepatic organic anion thauj polypeptide (OATP) nyob rau hauv cynomolgus liab.Drug Metab. Pharmacokinet.   30(2) , 198-204, (2015)
2. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) txo qis inflammatory angiogenesis hauv nas.APMIS   121(5) , 422-30, (2013)
3. Qhov cuam tshuam ntawm ntau hom statins ntawm kev loj hlob thiab kev tsiv teb tsaws ntawm HGF-induced Human Umbilical Vein Endothelial Cells (HUVECs).Eur. Rev. Med. Pharmacol. Sci.   17(21) , 2874-83, (2013)

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cerificate

 

 

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